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Pub. Date:
Taylor & Francis
The Microbiome and the Brain / Edition 1

The Microbiome and the Brain / Edition 1

by David Perlmutter


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Brain related disorders are among the most challenging health issues of our time. The development of effective therapeutic and preventive strategies for these disorders relies on a comprehensive understanding of the underlying causative mechanisms. And, until recently, these mechanisms have remained somewhat elusive.

The newly discovered pivotal role of the intestinal microbiome in brain health, functionality, and resistance to disease is revolutionizing neuroscience. The Microbiome and the Brain, through the contributions of some of the most forward thinking researchers and clinicians in the field, comprehensively reveals the leading edge of our understanding of the fundamental role of gut microbes and their metabolites in a wide array of seemingly diverse brain issues including Alzheimer’s disease, autism, multiple sclerosis, and mood disorders. In addition, mechanisms defining these relationships are explored along with a presentation of the state-of-the-art as it relates to interpretation of relevant laboratory assessments. Finally, novel therapeutic opportunities, derived from this exciting science are presented.

Readers will learn:

  • The highly validated relationship between alterations of gut microbes and their metabolites, and risk for Alzheimer’s disease.

  • The important link between autism and intestinal dysbiosis.

  • Appropriate interpretation of available laboratory assessments of the intestinal microbiome.

  • The potential role of fecal microbial transplant in neurological diseases.

  • The influence of diet and other lifestyle choices on the microbiome as it relates to brain health and functionality.

Product Details

ISBN-13: 9780815376729
Publisher: Taylor & Francis
Publication date: 12/09/2019
Pages: 240
Product dimensions: 6.12(w) x 9.25(h) x 0.00(d)

About the Author

Dr. Perlmutter is a Board-Certified Neurologist and Fellow of the American College of Nutrition who received his M.D. degree from the University of Miami School of Medicine where he was awarded the Leonard G. Rowntree Research Award. He has published extensively in peer-reviewed scientific journals including Archives of Neurology, Neurosurgery, and The Journal of Applied Nutrition, and is a frequent lecturer at symposia sponsored by such medical institutions as Columbia University, Scripps Institute, New York University, and Harvard University. He serves as Associate Professor at the University of Miami Miller School of Medicine.

Dr. Perlmutter has been interviewed on many nationally syndicated television programs including 20/20, Larry King Live, CNN, Fox News, Fox and Friends, The Today Show, Oprah, The Dr.Oz Show and The CBS Early Show. He is the recipient of the Linus Pauling Award for his innovative approaches to neurological disorders and in addition was awarded the Denham Harmon Award for his pioneering work in the application of free radical science to clinical medicine. He is the recipient of the 2006 National Nutritional Foods Association Clinician of the Year Award and was awarded the Humanitarian of the Year award from the American College of Nutrition in, 2010. In 2015 Dr. Perlmutter was awarded both the Media Award from the American College of Nutrition and the Healthy Living Award from The Invisible Disabilities Association.

Dr. Perlmutter is the author of seven books including the #1 New York Times Bestseller, Grain Brain, The Surprising Truth About Wheat, Carbs and Sugar - Your Brain’s Silent Killers, now with over 1 million copies in print and published in 27 countries.

His new book, Brain Maker: The Power of Gut Microbes to Heal and Protect Your Brain–for Life, is also a New York Times Bestseller and is now available nationwide.

Table of Contents

Emerging Technologies. Research Overview and Diagnostic Applications. Metadata and the Microbiome. Metabolic Effects of the Microbiome on the Brain. The Prenatal Microbiome in Health and Disease. Exercise. The Microbiome’s Indirect Effects on the Brain through Dysmetabolism and Diabetes. The Microbiome’s Indirect Effects on the Brain through Inflammatory Bowel Disease. The Microbiome and Neurologic Disease. Depression and Anxiety. Autism and Spectrum Disorders. ADHD. Alzheimer’s Disease as a Crisis of Microbial Diversity. Headache. Chronic Pain. Multiple Sclerosis. Movement Disorders. Translation into Clinical Practice.