Ophthalmic Drug Delivery Systems

Ophthalmic Drug Delivery Systems

by Taylor and Francis

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Overview

An in-depth reference which lays the groundwork for understanding constraints on the delivery of ophthalmic drugs, and surveys the delivery systems currently available or in various stages of research and development. The 21 chapters cover topics such as anterior and posterior segment microdialysis; ocular drug delivery; ophthalmic formulation design; treatment of retino-choroidal and retinal degenerative diseases; and the latest strategies in gene therapy, ocular microdialysis, vitreous drug disposition modeling, and receptor/transporter targeted drug delivery. For professionals or advanced students in medicine, veterinary medicine, pharmaceuticals, regulatory agencies, and related fields. Annotation ©2003 Book News, Inc., Portland, OR

Product Details

ISBN-13: 9780824788063
Publisher: Taylor & Francis
Publication date: 01/01/1993
Series: Drugs and the Pharmaceutical Sciences Series , #58
Pages: 520
Product dimensions: 7.48(w) x 10.24(h) x (d)

Table of Contents

"I: Fundamental Considerations 1. Overview of Ocular Drug Delivery 2. Membrane Transport Processes in the Eye 3. General Considerations in Ocular Drug Delivery II: Transport Models in Ocular Drug Delivery 4. Ocular Drug Transfer following Systemic Drug Administration 5. Ocular Pharmacokinetics and Pharmacodynamics 6. Mathematical Modeling of Drug Distribution in the Vitreous Humor 7. Anterior Segment Microdialysis 8. Posterior Segment Microdialysis III: Drug Delivery Systems 9. Ocular Penetration Enhancers 10. Corneal Collagen Shields for Ocular Drug Delivery 11. The Noncorneal Route in Ocular Drug Delivery 12. Ocular Iontophoresis 13. Mucoadhesive Polymers in Ophthalmic Drug Delivery 14. Microparticles and Nanoparticles in Ocular Drug Delivery 15. Dendrimers: An Innovative and Enhanced Ocular Drug Delivery System 16. Ocular Delivery and Therapeutics of Proteins and Peptides 17. Retinal Disease Models for Development of Drug and Gene Therapies
18. New Experimental Therapeutic Approaches for Degenerative Diseases of the Retina 19. Gene, Oligonucleotide, and Ribozyme Therapy in the Eye IV: Regulatory Aspects 20. Regulatory Considerations 21. Patent Considerations"

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