ISBN-10:
0306435446
ISBN-13:
9780306435447
Pub. Date:
01/31/1991
Publisher:
Springer US
Megakaryocytes, Platelets, Macrophages, and Eosinophils / Edition 1

Megakaryocytes, Platelets, Macrophages, and Eosinophils / Edition 1

by J. Robin HarrisJ. Robin Harris

Hardcover

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Overview

Blood Cell Biochemistry was initially conceived as part of the Plenum series Subcellular Biochemistry, from which it has developed into a separate series. The present volume is devoted primarily to contributions on megakaryocytes and platelets and, to a lesser extent, to macrophages and eosinophils. The book does not attempt a rigorous or total coverage of the particular topics; it represents the areas of current scientific activity and interest that were selected by the editor at the commencement of this project. In general, the approach has been similar to that adopted for Volume 1 of the series (Erythroid Cells); the same approach will be followed subsequently in Volume 3 (Lymphocytes and Granulocytes). This book opens with a developmentally oriented chapter by Janine Breton-Gorius on megakaryocyte maturation and platelet release in normal conditions, which serves to set the scene ultrastructurally for much of the data that follow. The biosynthesis and process­ ing of platelet glycoproteins in megakaryocytes is dealt with by Alain Duperray and his colleagues, and thereby provides an in-depth biochemical survey of the megakaryocyte. The applications and strengths of crossed immunoelectrophoresis for the study of platelet membrane proteins is then covered by Simon Karpatkin, and a detailed account of the heredity disorders of platelet function is provided by Francine Rendu and Evelyne Dupuy.

Product Details

ISBN-13: 9780306435447
Publisher: Springer US
Publication date: 01/31/1991
Series: Blood Cell Biochemistry , #2
Edition description: 1991
Pages: 349
Product dimensions: 6.14(w) x 9.21(h) x 0.03(d)

Table of Contents

1 Megakaryocyte Maturation and Platelet Release in Normal and Pathologic Conditions.- 2 Biosynthesis and Processing of Platelet Glycoproteins in Megakaryocytes.- 3 Crossed Immunoelectrophoresis for the Study of Platelet Membrane Proteins.- 4 Hereditary Disorders of Platelet Function.- 5 The Cytoskeleton of Human Blood Platelets.- 6 Immunological Studies of the Platelet Cytoskeleton.- 7 Effect of Lipoproteins and Platelets on Macrophage Cholesterol Metabolism.- 8 Macrophage Membrane: Structure and Function.- 9 Subcellular Morphology and Biochemistry of Eosinophils.

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