| Tye Sheridan | Watts / Parzival |
| Olivia Cooke | Samantha/ Art3mis |
| Ben Mendelsohn | Nolan Sorrento |
| T.J. Miller | I-ROk |
| Simon Pegg | Ogden Morrow |
| Mark Rylance | Anorak/Halliday |
| Hannah John-Kamen | F'Nale Zandor |
| Lena Waithe | Aech/Helen |
| Philip Zhao | Sho |
| Win Morisaki | Dalto |
| Ralph Ineson | Rick |
| Susan Lynch | Alice |
| Clare Higgins | Mrs. Gilmore |
| Laurence Spellman | Lame Tattoo Guy (Reb) |
| Perdita Weeks | Kira |
| Joel MacCormack | Sixer #6655 |
| Kit Connor | Reb Kid |
| Leo Heller | Reb Kid |
| Antonio Mattera | Reb Kid |
| Ronke Adekoluejo | Sorrento's Assistant |
| William Gross | Ten-Year-Old-Kid |
| Gareth Mason | Chubby Guy |
| Sandra Dickinson | Old Boxing Woman |
| Lynne Wilmot | Pole Dancer |
| Jayden Fowora-Knight | Boy Playing Tennis |
| Gavin Marshall | Shift Manager/Mocap Core Cast |
| Mark Stanley | Old Zombie Woman |
| Emily Beacock | Twin |
| Rosanna Beacock | Twin |
| Gem Refoufi | Pretty Naked Girl Body Double |
| Jane Leaney | Queen of Cats/Bathroom Zombie |
| Elliot Barnes-Worrell | Sixer #1 |
| Asan N'Jie | Sixer #5 |
| Robert Gilbert | Andrew (Sorrento's Head of Security) |
| Stephen Mitchell | Police Officer |
| Letitia Wright | Reb (Safe House) |
| Kae Alexander | Reb (Safe House) |
| Josh Jefferies | Mocap Core Cast/Sixer Instructor |
| Avye Leventis | Mocap Core Cast/Female Sixer #2 |
| Dean Street | Mocap Core Past |
| Michael Wildman | Sixer Drill Instructor |
| Turlough Convery | Chief Oology Expert |
| Joe Hurst | Oology Expert |
| Eric Sigmundsson | Oology Expert |
| James Dryden | Oology Expert |
| Danielle Phillips | Oology Expert |
| Rona Morison | Oology Expert |
| Khalil Madovi | Oology Expert |
| Bruce Lester-Johnson | IOI Board Member |
| Tom Turner | IOI Board Member |
| Paul Barnhill | Sorrento's Man |
| Isaac Andrews | Halliday 7 Years Old |
| Maeve Bluebell Wells | Female Sixer #1 |
| Naana Agyei Ampadu | Gospel Singer |
| Donovan Blackwood | Gospel Singer |
| Neet Mohan | Snacks (Bootsuit Commercial) |
| Georgie Farmer | Kid (Bootsuit Commercial) |
| Kathryn Wilder | Female Gamer (Bootsuit Commercial) |
| Sid Sagar | Regular Guy (Bootsuit Commercial) |
| David Forman | Hong Kong Businessman |
| Ian Davies | Police Officer (Stacks Explosion) |
| Lulu Wilson | Elementary Kid |
| Adolfo Alvarez | Elementary Kid |
| Alonso Alvarez | Elementary Kid |
| Jadah Marie | Elementary Kid |
| Dallas Young | Elementary Kid |
| McKenna Grace | Elementary Kid |
| Arianna Jaffier | High School Kid |
| Armani Jackson | High School Kid |
| Britain Dalton | High School Kid |
| Jacob Bertrand | High School Kid |
| Daniel Zolghadri | High School Kid |
| Sydney Brower | Girl in Bedroom at House |
| Cara Pifko | Leslee |
| Vic Chao | Goro |
| Cara Theobold | Tracer |
Technical Credits
| Steven Spielberg | Director,Producer |
| David Apgar | Animator |
| Aaron Barlow | Animator |
| Alexandre Belbari | Animator |
| Bruce Berman | Executive Producer |
| Lucy Bevan | Casting |
| Guy Bradley | Art Director |
| Sarah Broshar | Editor |
| Jean-Simon Chabot | Animator |
| Kathy Kit Ying Choi | Animator |
| Craig Christian | Animator |
| Ernest Cline | Screenwriter |
| Amaury Coljon | Animator |
| Neil Corbould | Special Effects Supervisor |
| Hunter Crowley | Sound Mixer |
| Chris De Faria | Executive Producer |
| Donald De Line | Producer |
| Cecile Dubois-Herry | Animator |
| Brendan Fagan | Animator |
| Fernando Falero | Animator |
| Dan Farah | Producer |
| Gavin Fitch | Art Director |
| Claire Fleming | Art Director |
| Jack Geckler | Animator |
| AJ Gillespie | Animator |
| Eduard Grigoryan | Animator |
| Huy Ho | Animator |
| Wong Joe | Animator |
| Suvi Jokiniemi | Animator |
| Jonathan Baker | Animator |
| Michael Kahn | Editor |
| Janusz Kaminski | Cinematographer |
| Kristie Macosko Krieger | Producer |
| Eduardo Lasierra | Animator |
| Ellen Lewis | Casting |
| Daniel Lupi | Executive Producer,Production Manager |
| Kyrsten Mate | Sound/Sound Designer |
| Jennifer Meislohn | Co-producer |
| Paul Munro | Sound Mixer |
| Niamh O'Loan | Makeup |
| Zak Penn | Screenwriter |
| Rahul Pokharkar | Animator |
| Stewart Probert | Production Manager |
| Roberto Raio | Animator |
| Stuart Rose | Art Director |
| Gary Rydstrom | Sound/Sound Designer |
| Alan Silvestri | Score Composer |
| Adam Somner | Asst. Director,Executive Producer |
| Adam Stockhausen | Production Designer |
| Remo Tozzi | Art Director |
| Kasia Walicka-Maimone | Costumes/Costume Designer |
