| Liam Hemsworth | Jake Morrison |
| Jeff Goldblum | David Levinson |
| Bill Pullman | President Whitmore |
| Maika Monroe | Patricia Whitmore |
| Travis Tope | Charlie |
| William Fichtner | General Adams |
| Charlotte Gainsbourg | Dr. Catherine Marceaux |
| Judd Hirsch | Julius Levinson |
| Jessie Usher | Dylan Hiller |
| Brent Spiner | Dr. Brakish Okun |
| Vivica A. Fox | Jasmine |
| Angelababy | Rain |
| Sela Ward | President Lanford |
| Grace Huang | Lin Tang |
| Joey King | Sam |
| Ryan Cartwright | Officer Ryan Collins |
| McKenna Grace | Daisy |
| Alice Rietveld | Secret Service Agent |
| Ava DelCielo | Young Mother |
| Gbenga Akinnagbe | Agent Matthew Travis |
| Joshua Mikel | Armand |
| Grizelda Quintana | Road Rage/Confrontation Driver |
| Chin Han | Commander Jiang Lao |
| Patrick St. Esprit | Secretary of Defense |
| Garrett Wareing | Bobby |
| Monique Candelaria | Tech Officer |
| Justin Raleigh | Creature Puppeteer |
| James A. Woods | Lt. Ritter |
| Morse Bicknell | Russian Commander |
| Nicolas Wright | Floyd Rosenberg |
| Alma Sisneros | Aide 2 |
| Deobia Oparei | Dikembe |
| John Storey | Dr. Isaacs |
| Ron Yuan | Yeong |
| Lance Lim | Kevin |
| Catharine Pilafas | Flight Officer #3 |
| Robert Neary | Captain McQuaide |
| Hays Wellford | Felix |
| Otis Winston | Brian Cole |
| Travis Hammer | Jeffrey Fineman |
| Kenny Leu | Ping Li |
| Stephen Oyoung | Young Man in Taxi |
| Beth Bailey | Nurse |
| Mark Falvo | News Reporter |
| Brandon Hampton | Officer |
| Omar Diop | Dikembe Guard |
| Stafford Douglas | Flight Officer #1 |
| Michael Love Toliver | Moon Base Tech |
| Sam Quinn | Radar Officer |
| Jacob Browne | Prison Tech 1 |
| Humberto Castro | Parisian Office Worker |
| Katrina Kavanaugh | ESD Tech |
| Robert Douglas Washington | Dirk Strickland |
| Stephen M. Hardin | Tug Pilot |
| Jade Kammerman | Orbital Tech |
| Auroroa Antonio | Teenager 1 |
| Diana Gaitirira | Comms Officer |
| Donovan Tyee Smith | Marcus |
| Gabriel Schmidt | Driver |
| Akshay Patel | Dylan's Pilot |
| David Devereaux | Military Aide #1 |
| Hans Obma | Sokolov |
| Shawn Lecrone | Area 51 Soldier Pvt. K. Ferguson |
| Marika Day | Panicked Patient |
| David Stanford | Washington D.C. Dignitary |
| Nate Warren | Marley Sullivan |
| Richard Beal | Military Brass |
| Danny Winn | DC Dignitary |
| Mark S. Allen | Journalist |
| Zeb Sanders | Henry |
| David Grant Wright | Military Aide |
| Nathan Brimmer | Cheyenne Mountain Security |
| Gregory Paul Valdez | Press Corps |
| Jacob Christopher Johnson | Teenager 2 |
| Christian Simpson | Sgt. Fletcher Smith |
| Jeffrey M. Williams | Patricia Squadron Pilot |
| Jerry Walker | Milky Eye Guard |
| Nathaniel Augustson | Gas Station Attendant |
| Jetto Dorsainville | Salt Flats Tech/Area 51 Soldier |
| Valerie Adams | Pedestrian |
| Jason E. Hill | Marine |
| Alexander Daniel Pimentel | Secret Service Agent |
| Dave Racki | Chopper Pilot |
| Vaughn Odenbrett | Angry Driver in Volvo Pulling Trailer |
| Faber Dewar | Flight Commander |
| Andrew James Bleidner | Area 51 Soldier |
| Matthew Munroe | Prison Tech #2 |
| Cory Kapahulehua | Moon Base Tug Pilot |
| Johnny Otto | Secret Service Agent |
| Edward Duran | Orbital Tech #2 |
| Jamie H. Jung | Ground Crew |
| Jonathan Lane | Press Corps |
| Andrei Lapionak | Russian Cosmonaut |
| Justin Arnsworth | Fighter Pilot |
| Raiden Integra | Press Corps |
| Brian Barela | Area 51 Soldier |
| John L. Grissom | War Room Commander |
| Colt Balok | Area 51 Soldier |
| Patrick Juarez | Area 51 Officer |
Technical Credits
| Roland Emmerich | Director,Original Story,Producer,Screenwriter |
| Lauren Abiouness | Art Director |
| Matt Akey | Executive Producer |
| Balaji Anbalagan | Animator |
| Ernie Avila | Set Decoration/Design |
| Chad Baalbergen | Special Effects |
| Friska Bako | Animator |
| Ravi Bansal | Art Director |
| Ruben Bautista | Special Effects |
| Jo Edna Boldin | Casting |
| Scott Beharrell Bono | Animator |
| Allan Cabal | Animator |
| Mary Castor | Makeup |
| Vincent Caudeville | Animator |
| Wesley Chandler | Animator |
| Aric Cheng | Set Decoration/Design |
| Lisy Christl | Costumes/Costume Designer |
| Barry Chusid | Production Designer |
| Peter Clayton | Animator |
| Michael Coldewey | Executive Producer |
| François Daignault | Camera Operator |
| Dean Devlin | Original Story,Producer,Screenwriter |
| Ümit Dönmez | Animator |
| Patrick Dunn-Baker | Set Decoration/Design |
| Denis Dvoryankin | Animator |
| Areito Echevarria | Special Effects |
| Ute Emmerich | Executive Producer |
| Volker Engel | Co-producer |
| Hartmut Engel | Animator |
| Thomas Enjalbert | Animator |
| Jason Fittipaldi | Animator |
| John Fleming | Special Effects |
| Markus Förderer | Cinematographer |
| Larry Franco | Executive Producer |
| Pedram Goshtasbpour | Animator |
| Sandra Guarda | Animator |
| Luis Guggenberger | Art Director |
| Toby Michael Haruno | Animator |
| Jim Hewitt | Set Decoration/Design |
| K.C. Hodenfield | Asst. Director |
| Mark Hofeling | Art Director |
| Patrick Kern | Animator |
| Thilo Kienle | Animator |
| Hye Sook Kim | Animator |
| Harald Kloser | Score Composer,Producer |
| Dorian Knapp | Animator |
| George R. Lee | Set Decoration/Design |
| Paul Lee | Animator |
| Carsten H.W. Lorenz | Executive Producer |
| Eduardo Castells Mateo | Animator |
| Caty Maxey | Art Director |
| Kenneth Meyer | Animator |
| Christa Munro | Art Director |
| Kevin O'Sullivan | Animator |
| Jessica Ott | Animator |
| Paul N.J. Ottosson | Sound/Sound Designer |
| Sam Page | Set Decoration/Design |
| Christopher Page | Animator |
| John Papsidera | Casting |
| Brooke Peters | Set Decoration/Design |
| Jordan Pitchon | Animator |
| Anne Porter | Set Decoration/Design |
| Jack Preston | Animator |
| Mathias Reiche | Animator |
| Shane Richards | Animator |
| Richard Roles | Camera Operator |
| Siobhan Roome | Set Decoration/Design |
| Sara Roybal | Makeup |
| Marco Rubeo | Set Decoration/Design |
| Dan Santos | Animator |
| Brett Schroeder | Animator |
| Michael Schulz | Animator |
| Divyesh Jagdish Shah | Animator |
| Marco Shepherd | Co-producer |
| Keith W. Smith | Animator |
| Chris Sokalofsky | Animator |
| Paul Sonski | Set Decoration/Design |
| Patrick M. Sullivan | Art Director |
| Eric P. Sundahl | Art Director |
| Kathie Talbot | Sound/Sound Designer |
| Tammy Smith | Animator |
| Isaac Hai Swee Tan | Animator |
| Danny Gordon Taylor | Animator |
| Sawan Thakrar | Animator |
| Andrew Thompson | Animator |
| Stuart Gordon Tribble | Makeup |
| Claudius Urban | Animator |
| James Vanderbilt | Screenwriter |
| William Rocky Vanoost | Animator |
| Clint Wallace | Art Director |
| Jo Walls | Animator |
| Thomas Wanker | Score Composer |
| Cameron Ward | Animator |
| Nakoma Whobrey | Makeup |
| Toby Winder | Animator |
| Adam Wolfe | Editor |
| James A. Woods | Original Story,Screenwriter |
| Simon Wottge | Animator |
| Nicolas Wright | Screenwriter |
| Nicholas Wright | Original Story |
