Private detective Franchot Tone is hired by a prominent politician (Tom Powers) to run a background check on the politician's wife (Lynn Merrick). Meanwhile, another client (Janet Blair) engages Tone to locate her missing sister-in-law. The two assignments merge into one before long, and Tone is up to his ears in the trouble he claims to love in the film's title. Like most movie private eyes, Tone attracts women like a magnet: In addition to the aforementioned Lynn Merrick and Janet Blair, the cast includes Glenda Farrell (as the p.i.'s faithful secretary), Janis Carter and Adele Jergens. I Love Trouble was based on The Double Take, a novel by Roy Higgins.