Writer/actor Spalding Gray is best known for his lengthy and insightful and sharply humorous onstage monologues, two of which, Swimming to Cambodia and Monster in a Box, have been filmed and released theatrically. Gray's Anatomy is also a filmed performance of a monologue he performed in 1993. Whereas the other two films had a focus on satire and humor, this one is a little more serious. Unlike the other two movies, it is less stagey and contains some interesting visuals and even a couple of interviews. The subject is Gray's bout with an eye ailment that caused him to go upon a world-wide journey in order to find a treatment alternative to the surgery he so feared and objected to on religious grounds.