| D.J. Cotrona | Flint |
| Dwayne Johnson | Hercules,Paul Doyle |
| Mark Wahlberg | Daniel Lugo |
| Ian McShane | Amphiaraus |
| Lee Byung-hun | Storm Shadow |
| Adrianne Palicki | Jaye |
| Anthony Mackie | Adrian Doorbal |
| John Hurt | Lord Cotys |
| Ray Park | Snake Eyes |
| Rufus Sewell | Autolycus |
| Tony Shalhoub | Victor Kershaw |
| Aksel Hennie | Tydeus |
| Ed Harris | Ed Dubois |
| Jonathan Pryce | President |
| Ingrid Bolsø Berdal | Atalanta |
| Rob Corddry | John Mese |
| RZA | The Blind Master |
| Ray Stevenson | Firefly |
| Channing Tatum | Duke |
| Elodie Yung | Jinx |
| Bruce Willis | General Joe Colton |
Technical Credits
| Brett Ratner | Director |
| Jon M. Chu | Director |
| Michael Bay | Director |
