Pill poppin' truckers provide the focus of this anti-drug drama. Much of the story centers upon an investigator for the US Food and Drug Department who has been assigned to stop all truckers from taking amphetamines while they drive. The drivers take the pills to help them stay awake on long-hauls. Unfortunately, the "speed" is also causing major accidents. The investigator goes undercover as a driver to help find the main drug pushers. En route he falls for a beautiful woman. Unfortunately, he finds that she is one of the biggest pushers in the country. Though the film's original intent was very serious, it has become popular with fans of campy or cult films.