This up-to-date work describes the large number of new antitumor antibiotics that have been discovered and evaluated since the first volume of The Chemistry of Antitumor Antibiotics was published in 1978. Covers the results of mode and action studies which have benefitted from high-field NMR, including 2-D techniques, computer modelling, and DNA sequencing methods. Also notes how biosynthesis has been helped by NMR to follow the incorporation of compounds containing stable isotopes.
About the Author
William A. Remers is the author of The Chemistry of Antitumor Antibiotics, Volume 2, published by Wiley.
Table of ContentsStreptozocin.
Pyrrolo (1,4) Benzodiazepines.
Saframycins, Renieramycins, and Safracins.
Naphthyridinomycin, Cyanocyclines, and Quinocarcin.
Nogalamycin and Related Compounds.
Streptonigrin and Lavendamycin.