ISBN-10:
012022481X
ISBN-13:
9780120224814
Pub. Date:
11/28/2003
Publisher:
Elsevier Science
Advances in Immunology

Advances in Immunology

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Overview

Advances in Immunology, Volume 146, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release focusing on The design of vaccine strategies to elicit HIV-1 broadly neutralizing antibodies, T cells in latent viral infections, Preserving Immune Homeostasis with A20, Transcriptional control in the context of innate and adaptive lymphoid development, RAG and AID structural biology and the important insights it has generated for the V(D)J recombination and CSR/SHM fields, and more.




  • Presents current developments and comprehensive reviews in immunology
  • Provides the latest in a longstanding, respected serial on the subject matter
  • Focuses on recent advances in the advancing area of the mechanisms involved in the evolution of HIV-1 neutralizing antibodies

Product Details

ISBN-13: 9780120224814
Publisher: Elsevier Science
Publication date: 11/28/2003
Series: Advances in Immunology Series , #81
Pages: 388
Product dimensions: 5.96(w) x 9.24(h) x 0.89(d)

About the Author

Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.

Table of Contents

1. The design of vaccine strategies to elicit HIV-1 broadly neutralizing antibodies Joseph Jardine 2. T cells in latent viral infections Dietmar Zehn 3. Preserving Immune Homeostasis with A20 Averil Ma 4. Transcriptional control in the context of innate and adaptive lymphoid development Barbara Kee 5. RAG and AID structural biology and the important insights it has generated for the V(D)J recombination and CSR/SHM fields Heng Ru 6. The advancing area of the mechanisms involved in the evolution of HIV-1 neutralizing antibodies Mattia Bonsignori 7. Normal Microbiota inducing disease Martin Kriegel 8. Plasma Cell Sub-populations Wolfgang Schuh

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